Elimination of Serum Free and Total Prostate-Specific Antigen after Radical Retropubic Prostatectomy
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چکیده
منابع مشابه
Elimination of serum free and total prostate-specific antigen after radical retropubic prostatectomy.
Elimination kinetics of serum total and free prostate-specific antigen were studied for a ten days course after radical retropubic prostatectomy on 11 patients suffering from organ confined prostate cancer. Samples were taken before operation, immediately after finishing the operation and 1, 2, 3, 4, 5, 6 h after prostatectomy and then once a day for the following ten days. The measurements wer...
متن کاملIs preoperative serum prostate-specific antigen level significantly related to clinical recurrence after radical retropubic prostatectomy for localized prostate cancer?
OBJECTIVE To evaluate the influence of preoperative serum prostate-specific antigen (PSA) level and other clinicopathological variables on the probability of biochemical failure and clinical recurrence after radical prostatectomy (RP) for localized prostate cancer. PATIENTS AND METHODS The study was a retrospective survival analysis in 211 patients undergoing retropubic RP for clinically loca...
متن کاملProstate specific antigen recurrence rates are low after radical retropubic prostatectomy and positive margins.
PURPOSE Treatment in patients with a positive surgical margin after radical retropubic prostatectomy is controversial. Options are observation, radiation therapy and early hormone therapy. Making the appropriate choice should be based on an understanding of the risk of recurrence without treatment. MATERIALS AND METHODS We reviewed the records of 1,383 patients after radical retropubic prosta...
متن کاملBiological half-life of prostate-specific antigen after radical prostatectomy.
The disappearance pattern of prostate-specific antigen from serum after a standard radical prostatectomy was studied in eight patients with cancer confined to the prostate. The results were used to plot an elimination curve and calculate the best fit. A biphasic pattern was found with an average biological half-life of 1.63 hours in the alpha-phase, and 4.63 days in the beta-phase. Based on the...
متن کاملSerum half-life time determination of free and total prostate-specific antigen following radical prostatectomy--a critical assessment.
OBJECTIVES All studies investigating the elimination kinetics of serum total (tPSA) and free (fPSA) prostate-specific antigen (PSA) were carried out in men undergoing radical prostatectomy. Radical prostatectomy itself could, however, have a major influence on the serum concentration of these tumor markers (e.g., perioperative fluid shift or blood loss). The purpose of our study was to determin...
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ژورنال
عنوان ژورنال: Clinical Chemistry and Laboratory Medicine
سال: 1997
ISSN: 1434-6621,1437-4331
DOI: 10.1515/cclm.1997.35.8.591